The Substance (2024) runs 2 h 21 min, is rated R in the US and averages 7.1 from 6,746 TMDB members. A fading celebrity decides to use a black market drug, a cell-replicating substance that temporarily creates a younger, better version of herself.
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Streaming availability by JustWatch. In the US, as of 2026-11-04: Hulu (subscription), MUBI (subscription), MUBI Amazon Channel (subscription).
The Substance on TMDB · This product uses the TMDB API but is not endorsed or certified by TMDB.

Lights Down is a free tool: tell it your streaming services and how long you have, and it ranks what you can stream tonight, with a this-or-that, a roll, a bracket and a wheel. Movie data from TMDB; streaming availability by JustWatch. Page updated 2026-11-04. This product uses the TMDB API but is not endorsed or certified by TMDB. Lights Down is a Somebody Decide program. How the data works · Legal & privacy · Tonight's lists